In 1854 on St. Mark´s day, the 25th April, the “St. Marks´s
Hospital for Fistula and other Diseases of the Rectum” was opened at City Road in London in a dedicated new building with 25 beds. Within the next decades, the speciality of colo-proctology was developed by
Frederick Salmon and other surgeons at St Mark´s. In 1897, a first extension to the Hospital was built. After the first world war a decision was taken for a second expansion, up to 93 beds, and “cancer” was
added to the Hospital´s title.
In 1922, GastroIntestinal Pathology was established at St Mark´s Hospital in London with the appointment of Cuthbert Dukes. Research became an integral part of the
hospital´s work. All surgical specimen of rectal cancer were carefully dissected. With the support of HJ Richard Bussey (since 1924), Dukes became a pioneer in staging the spread of rectal cancer: until
today, the “Dukes´staging” is popular.
From 1956, Basil Morson
has developed Gastrointestinal Pathology as a new subspeciality. In 1972, Morson and Dawson published the first textbook in this field. After his retirement he was succeeded by Jeremy Jass
(from 1986-1990) and Ian Talbot (from 1990).
In 1995, St Mark´s Hospital moved from its time honoured building in East London to Harrow in NorthWest London. There the former St Mark´s
Department of G I Pathology has been merged with the Department of Cellular Pathology of the NorthWest London Hospitals NHS Trust